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Aminodi(hetero)arylamines in the Thieno[3,2-b]pyridine Series: Synthesis, Effects in Human Tumor Cells Growth, Cell Cycle Analysis, Apoptosis and Evaluation of Toxicity Using Non-Tumor Cells
Three aminodi(hetero)arylamines were prepared via a palladium-catalyzed C-N Buchwald-Hartwig coupling of methyl 3-aminothieno[3,2-b]pyridine-2-carboxylate with different bromonitrobenzenes, followed by reduction of the nitro groups of the coupling products to the corresponding amino compounds. The a...
Autores principales: | Calhelha, Ricardo C., Ferreira, Isabel C. F. R., Peixoto, Daniela, Abreu, Rui M. V., Vale-Silva, Luís A., Pinto, Eugénia, Lima, Raquel T., Alvelos, M. Inês, Vasconcelos, M. Helena, Queiroz, Maria-João R. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268773/ https://www.ncbi.nlm.nih.gov/pubmed/22456543 http://dx.doi.org/10.3390/molecules17043834 |
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