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Synthesis, Antigenicity Against Human Sera and Structure-Activity Relationships of Carbohydrate Moieties from Toxocara larvae and Their Analogues

Stereocontrolled syntheses of biotin-labeled oligosaccharide portions containing the Galβ1-3GalNAc core of the TES-glycoprotein antigen obtained from larvae of the parasite Toxocara and their analogues have been accomplished. Trisaccharides Fuc2Meα1-2Gal4Meβ1-3GalNAcα1-OR (A), Fucα1-2Gal4Meβ1-3GalNA...

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Detalles Bibliográficos
Autores principales: Koizumi, Akihiko, Yamano, Kimiaki, Tsuchiya, Takashi, Schweizer, Frank, Kiuchi, Fumiyuki, Hada, Noriyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268804/
https://www.ncbi.nlm.nih.gov/pubmed/22847142
http://dx.doi.org/10.3390/molecules17089023