Astragalus Polysaccharide Improves Palmitate-Induced Insulin Resistance by Inhibiting PTP1B and NF-κB in C2C12 Myotubes

We investigated the effects of Astragalus polysaccharide (APS) on palmitate-induced insulin resistance in C2C12 skeletal muscle myotubes. Palmitate-reduced glucose uptake was restored by APS. APS prevented palmitate-induced C2C12 myotubes from impaired insulin signaling by inhibiting Ser307 phosphor...

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Detalles Bibliográficos
Autores principales: Zhao, Ming, Zhang, Zhao-Feng, Ding, Ye, Wang, Jun-Bo, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268810/
https://www.ncbi.nlm.nih.gov/pubmed/22728372
http://dx.doi.org/10.3390/molecules17067083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268810/
https://www.ncbi.nlm.nih.gov/pubmed/22728372
http://dx.doi.org/10.3390/molecules17067083

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