Ultrasound Irradiation Promoted Enzymatic Transesterification of (R/S)-1-Chloro-3-(1-naphthyloxy)-2-propanol

(R)-1-Chloro-3-(1-naphthyloxy)-2-propanol (3), which is the key intermediate of (S)-propranolol, was successfully prepared via enantioselective transesterification catalyzed by lipase under ultrasound irradiation. Compared with conventional shaking, the enzyme activity and enantioselectivity were dr...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Zhang, Hong, Wang, Jiaxin, Chen, Ge, Fang, Xuedong, Wang, Zhi, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268847/
https://www.ncbi.nlm.nih.gov/pubmed/22964502
http://dx.doi.org/10.3390/molecules170910864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268847/
https://www.ncbi.nlm.nih.gov/pubmed/22964502
http://dx.doi.org/10.3390/molecules170910864

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