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Synthesis and in Vitro Cytotoxic Evaluation of Aminoquinones Structurally Related to Marine Isoquinolinequinones

The synthesis of 4-methoxycarbonyl-3-methylisoquinolinequinone (1) and a variety of its substitution products with amino-, alkylamino and halogen groups on the quinone nucleus is reported. The series of 6-, 7- and 6,7-subtituted isoquinolinequinones were evaluated in vitro for their cytotoxic activi...

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Detalles Bibliográficos
Autores principales: Delgado, Virginia, Ibacache, Andrea, Theoduloz, Cristina, Valderrama, Jaime A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268849/
https://www.ncbi.nlm.nih.gov/pubmed/22678417
http://dx.doi.org/10.3390/molecules17067042