Novel Coumarin Derivatives Containing 1,2,4-Triazole, 4,5-Dicyanoimidazole and Purine Moieties: Synthesis and Evaluation of Their Cytostatic Activity

We report here on the synthesis and in vitro anti-tumor effects of a series of novel 1,2,4-triazole (compounds 3–6), 4,5-dicyanoimidazole (compound 7), and purine (compounds 8–13) coumarin derivatives and their acyclic nucleoside analogues 14–18. Structures of novel compounds 3–18 were deduced from...

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Detalles Bibliográficos
Autores principales: Benci, Krešimir, Mandić, Leo, Suhina, Tomislav, Sedić, Mirela, Klobučar, Marko, Pavelić, Sandra Kraljević, Pavelić, Krešimir, Wittine, Karlo, Mintas, Mladen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268888/
https://www.ncbi.nlm.nih.gov/pubmed/22971585
http://dx.doi.org/10.3390/molecules170911010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268888/
https://www.ncbi.nlm.nih.gov/pubmed/22971585
http://dx.doi.org/10.3390/molecules170911010

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