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Synthesis of New Macrocyclic Polyamides as Antimicrobial Agent Candidates

A series of macrocyclic imides and Schiff-bases have been prepared via the cyclocondensation of pyridine-2,6-dicarbonyl dichloride (1) with L-ornithine methyl ester to give the corresponding macrocyclic bisester 2. Treatment of 2 with hydrazine hydrate gave macrocyclic bisacid hydrazide 3, which was...

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Detalles Bibliográficos
Autores principales: El-Salam, Osama I. Abd, Al-Omar, Mohamed A., Fayed, Ahmed A., Flefel, Eman M., Amr, Abd El-Galil E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268893/
https://www.ncbi.nlm.nih.gov/pubmed/23222868
http://dx.doi.org/10.3390/molecules171214510