Synthesis of Highly Substituted Oxazoles through Iodine(III)-Mediated Reactions of Ketones with Nitriles

In the presence of trifluoromethanesulfonic acid (TfOH) or bis(trifluoromethane-sulfonyl)imide (Tf(2)NH), iodosobenzene (PhI=O) efficiently promoted the reactions of dicarbonyl compounds as well as monocarbonyl compounds with nitriles to give 2,4-disubstituted and 2,4,5-trisubstituted oxazole in a s...

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Detalles Bibliográficos
Autores principales: Saito, Akio, Hyodo, Nao, Hanzawa, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268898/
https://www.ncbi.nlm.nih.gov/pubmed/22976468
http://dx.doi.org/10.3390/molecules170911046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268898/
https://www.ncbi.nlm.nih.gov/pubmed/22976468
http://dx.doi.org/10.3390/molecules170911046

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