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Chiral Flavanones from Amygdalus lycioides Spach: Structural Elucidation and Identification of TNFalpha Inhibitors by Bioactivity-guided Fractionation

Phytochemical investigation on the Amygdalus lycioides Spach branchelets resulted in the isolation of four chiral flavanones: (2R,3R)-Taxifolin, (2R,3R)-aromadendrin, (S)-5,7,3',5'-tetrahydroxyflavanone and (S)-naringenin. The flavanones were isolated by semi-preparative HPLC, their struct...

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Detalles Bibliográficos
Autores principales: Gaggeri, Raffaella, Rossi, Daniela, Christodoulou, Michael S., Passarella, Daniele, Leoni, Flavio, Azzolina, Ornella, Collina, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268923/
https://www.ncbi.nlm.nih.gov/pubmed/22318322
http://dx.doi.org/10.3390/molecules17021665