Synthesis of 1,2,3-Triazole Derivatives and in Vitro Antifungal Evaluation on Candida Strains

1,2,3-Triazoles have been extensively studied as compounds possessing important biological activities. In this work, we describe the synthesis of ten 2-(1-aryl-1H-1,2,3-triazol-4-yl)propan-2-ols via copper catalyzed azide alkyne cycloaddition (CuAAc or click chemistry). Next thein vitro antifungal a...

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Detalles Bibliográficos
Autores principales: Lima-Neto, Reginaldo G., Cavalcante, Nery N. M., Srivastava, Rajendra M., Mendonça Junior, Francisco J. B., Wanderley, Almir G., Neves, Rejane P., dos Anjos, Janaína V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268928/
https://www.ncbi.nlm.nih.gov/pubmed/22592091
http://dx.doi.org/10.3390/molecules17055882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268928/
https://www.ncbi.nlm.nih.gov/pubmed/22592091
http://dx.doi.org/10.3390/molecules17055882

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