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Synthesis and Antimicrobial Activity of Some New Pyrimidinone and Oxazinone Derivatives Fused with Thiophene Rings Using 2-Chloro-6-ethoxy-4-acetylpyridine as Starting Material

A series of pyridines, pyrimidinones, oxazinones and their derivatives were synthesized as antimicrobial agents using citrazinic acid (2,6-dihydroxyisonicotinic acid) as a starting material. α,β-Unsaturated ketones 3a–c were condensed with cyanothio-acetamide in the presence of ammonium acetate to g...

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Detalles Bibliográficos
Autores principales: Hossan, Aisha S. M., Abu-Melha, Hanaa M. A., Al-Omar, Mohamed A., Amr, Abd El-Galil E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268936/
https://www.ncbi.nlm.nih.gov/pubmed/23165308
http://dx.doi.org/10.3390/molecules171113642