The Binding Affinity and Molecular Basis of the Structure-Binding Relationship between Urinary Tamm-Horsfall Glycoprotein and Tumor Necrosis Factor-α

In a previous study we noted significant THP binding to TNF-α, but did not explore the molecular basis of the structure-binding relationship. In this study, we used lectin-binding ELISA to assess the carbohydrate compositions of THP, BSA, IgG, TNF-α, and IFN-γ. We identified β(1,4)-N-acetylglucosami...

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Detalles Bibliográficos
Autores principales: Wu, Cheng-Han, Li, Ko-Jen, Siao, Sue-Cien, Chen, Yu-Hsuan, Wu, Tsai-Hung, Tsai, Chang-Youh, Yu, Chia-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268941/
https://www.ncbi.nlm.nih.gov/pubmed/23060289
http://dx.doi.org/10.3390/molecules171011978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268941/
https://www.ncbi.nlm.nih.gov/pubmed/23060289
http://dx.doi.org/10.3390/molecules171011978

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