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The Binding Affinity and Molecular Basis of the Structure-Binding Relationship between Urinary Tamm-Horsfall Glycoprotein and Tumor Necrosis Factor-α
In a previous study we noted significant THP binding to TNF-α, but did not explore the molecular basis of the structure-binding relationship. In this study, we used lectin-binding ELISA to assess the carbohydrate compositions of THP, BSA, IgG, TNF-α, and IFN-γ. We identified β(1,4)-N-acetylglucosami...
Autores principales: | Wu, Cheng-Han, Li, Ko-Jen, Siao, Sue-Cien, Chen, Yu-Hsuan, Wu, Tsai-Hung, Tsai, Chang-Youh, Yu, Chia-Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268941/ https://www.ncbi.nlm.nih.gov/pubmed/23060289 http://dx.doi.org/10.3390/molecules171011978 |
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