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Oxime Esters of 2,6-Diazaanthracene-9,10-dione and 4,5-Diazafluoren-9-one as Photo-induced DNA-Cleaving Agents

Two series of oxime esters containing the 2,6-diazaanthracene-9,10-dione bis-(O-benzoyloxime) and 4,5-diazafluoren-9-one O-9-benzoyloxime moieties have been synthesized and tested as photo-induced DNA cleaving agents. All these compounds were found to cleave DNA upon irradiation with 312 nm UV light...

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Detalles Bibliográficos
Autores principales: Chou, Shang-Shing P., Juan, Jui-Chi, Tsay, Shwu-Chen, Huang, Kuei Pin, Hwu, Jih Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268963/
https://www.ncbi.nlm.nih.gov/pubmed/22421791
http://dx.doi.org/10.3390/molecules17033370