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Impact of Halogen Substituents on Interactions between 2-Phenyl-2,3-dihydroqulinazolin-4(1H)-one Derivatives and Human Serum Albumin

A novel type of 2-(un)substituted phenyl-2,3-dihydroquinazolin-4(1H)-one (DQL) derivatives were designed and synthesized to study the impact of halogen substituents on interactions between DQL and human serum albumin (HSA) by comparison methodology. The interactions between DQL and HSA were studied...

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Detalles Bibliográficos
Autores principales: Liu, Feng, Wang, Yi, Lv, Cong, Wang, Lei, Ou, Junjun, Wang, Min, Liu, Shangzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268991/
https://www.ncbi.nlm.nih.gov/pubmed/22343405
http://dx.doi.org/10.3390/molecules17022000