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Therapeutic Applications of Nucleic Acids and Their Analogues in Toll-like Receptor Signaling

Toll-like receptors (TLRs) belong to a family of innate immune receptors that detect and clear invading microbial pathogens. Specifically intracellular TLRs such as TLR3, TLR7, TLR8 and TLR9 recognize nucleic acids such as double-stranded RNA, single-stranded RNA and CpG DNA respectively derived fro...

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Detalles Bibliográficos
Autores principales: Gosu, Vijayakumar, Basith, Shaherin, Kwon, O-Pil, Choi, Sangdun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269001/
https://www.ncbi.nlm.nih.gov/pubmed/23151919
http://dx.doi.org/10.3390/molecules171113503