Computational Prediction of Blood-Brain Barrier Permeability Using Decision Tree Induction

Predicting blood-brain barrier (BBB) permeability is essential to drug development, as a molecule cannot exhibit pharmacological activity within the brain parenchyma without first transiting this barrier. Understanding the process of permeation, however, is complicated by a combination of both limit...

Descripción completa

Detalles Bibliográficos
Autores principales: Suenderhauf, Claudia, Hammann, Felix, Huwyler, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269008/
https://www.ncbi.nlm.nih.gov/pubmed/22941223
http://dx.doi.org/10.3390/molecules170910429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269008/
https://www.ncbi.nlm.nih.gov/pubmed/22941223
http://dx.doi.org/10.3390/molecules170910429

Ejemplares similares