Design, Synthesis and Antifibrotic Activities of Carbohydrate- Modified 1-(Substituted aryl)-5-trifluoromethyl-2(1H) Pyridones

Pirfenidone, a pyridone compound, is an effective and novel antifibrotic agent. In this article, we describe the design, synthesis and activity evaluation of novel antifibrotic agents, 1-(substituted aryl)-5-trifluoromethyl-2(1H) pyridones modified with carbohydrate. Most of the title compounds exhi...

Descripción completa

Detalles Bibliográficos
Autores principales: Lou, Qinghua, Meng, Xiangbao, Lao, Zhiqi, Xuan, Lingling, Bai, Jinye, Hou, Qi, Hu, Gaoyun, Luo, Renna, Tao, Lijian, Li, Zhongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269014/
https://www.ncbi.nlm.nih.gov/pubmed/22252504
http://dx.doi.org/10.3390/molecules17010884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269014/
https://www.ncbi.nlm.nih.gov/pubmed/22252504
http://dx.doi.org/10.3390/molecules17010884

Ejemplares similares