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Design, Synthesis and Antifibrotic Activities of Carbohydrate- Modified 1-(Substituted aryl)-5-trifluoromethyl-2(1H) Pyridones

Pirfenidone, a pyridone compound, is an effective and novel antifibrotic agent. In this article, we describe the design, synthesis and activity evaluation of novel antifibrotic agents, 1-(substituted aryl)-5-trifluoromethyl-2(1H) pyridones modified with carbohydrate. Most of the title compounds exhi...

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Detalles Bibliográficos
Autores principales:	Lou, Qinghua, Meng, Xiangbao, Lao, Zhiqi, Xuan, Lingling, Bai, Jinye, Hou, Qi, Hu, Gaoyun, Luo, Renna, Tao, Lijian, Li, Zhongjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269014/ https://www.ncbi.nlm.nih.gov/pubmed/22252504 http://dx.doi.org/10.3390/molecules17010884

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