Synthesis, DNA-Binding and Antiproliferative Properties of Acridine and 5-Methylacridine Derivatives

Several acridine derivatives were synthesized and their anti-proliferative activity was determined. The most active molecules were derivatives of 5-methylacridine-4-carboxylic acid. The DNA binding properties of the synthesized acridines were analyzed by competitive dialysis and compared with the an...

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Detalles Bibliográficos
Autores principales: Ferreira, Rubén, Aviñó, Anna, Mazzini, Stefania, Eritja, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269017/
https://www.ncbi.nlm.nih.gov/pubmed/22683895
http://dx.doi.org/10.3390/molecules17067067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269017/
https://www.ncbi.nlm.nih.gov/pubmed/22683895
http://dx.doi.org/10.3390/molecules17067067

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