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Synthesis, DNA-Binding and Antiproliferative Properties of Acridine and 5-Methylacridine Derivatives

Several acridine derivatives were synthesized and their anti-proliferative activity was determined. The most active molecules were derivatives of 5-methylacridine-4-carboxylic acid. The DNA binding properties of the synthesized acridines were analyzed by competitive dialysis and compared with the an...

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Detalles Bibliográficos
Autores principales:	Ferreira, Rubén, Aviñó, Anna, Mazzini, Stefania, Eritja, Ramon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269017/ https://www.ncbi.nlm.nih.gov/pubmed/22683895 http://dx.doi.org/10.3390/molecules17067067

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