Synthesis and Antitumor Evaluation of 6-Aryl-substituted benzo[j]phenanthridine- and Benzo[g]pyrimido[4,5-c]isoquinolinequinones

A variety of novel 6-arylsubstituted benzo[j]phenanthridine- and benzo[g]-pyrimido[4,5-c]isoquinolinequinones were synthesized from 1,4-naphthoquinone, aryl-aldehydes and enaminones via a two-step synthetic approach. The cytotoxic activity of the aminoquinone derivatives was evaluated in vitro again...

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Detalles Bibliográficos
Autores principales: Iribarra, Jennyfer, Vásquez, David, Theoduloz, Cristina, Benites, Julio, Ríos, David, Valderrama, Jaime A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269025/
https://www.ncbi.nlm.nih.gov/pubmed/23023687
http://dx.doi.org/10.3390/molecules171011616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269025/
https://www.ncbi.nlm.nih.gov/pubmed/23023687
http://dx.doi.org/10.3390/molecules171011616

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