Effects of a Natural Prolyl Oligopeptidase Inhibitor, Rosmarinic Acid, on Lipopolysaccharide-Induced Acute Lung Injury in Mice

Rosmarinic acid (RA), a polyphenolic phytochemical, is a natural prolyl oligopeptidase inhibitor. In the present study, we found that RA exerted potent anti-inflammatory effects in in vivo models of acute lung injury (ALI) induced by lipopolysaccharide (LPS). Mice were pretreated with RA one hour be...

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Detalles Bibliográficos
Autores principales: Chu, Xiao, Ci, Xinxin, He, Jiakang, Jiang, Lanxiang, Wei, Miaomiao, Cao, Qingjun, Guan, Mingfeng, Xie, Xianxing, Deng, Xuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269028/
https://www.ncbi.nlm.nih.gov/pubmed/22441336
http://dx.doi.org/10.3390/molecules17033586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269028/
https://www.ncbi.nlm.nih.gov/pubmed/22441336
http://dx.doi.org/10.3390/molecules17033586

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