Synthesis of 1,4-Disubstituted Mono and Bis-triazolocarbo-acyclonucleoside Analogues of 9-(4-Hydroxybutyl)guanine by Cu(I)-Catalyzed Click Azide-Alkyne Cycloaddition

A series of novel mono-1,2,3-triazole and bis-1,2,3-triazole acyclonucleoside analogues of 9-(4-hydroxybutyl)guanine was prepared via copper(I)-catalyzed 1,3-dipolar cycloaddition of N-9 propargylpurine, N-1-propargylpyrimidines/as-triazine with the azido-pseudo-sugar 4-azidobutylacetate under solve...

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Detalles Bibliográficos
Autores principales: Krim, Jamal, Taourirte, Moha, Engels, Joachim W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269037/
https://www.ncbi.nlm.nih.gov/pubmed/22202806
http://dx.doi.org/10.3390/molecules17010179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269037/
https://www.ncbi.nlm.nih.gov/pubmed/22202806
http://dx.doi.org/10.3390/molecules17010179

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