Synthesis and Cytotoxicity Testing of New Amido-Substituted Triazolopyrrolo[2,1-c][1,4]benzodiazepine (PBDT) Derivatives

A series of amido-substituted triazolopyrrolo[2,1-c][1,4]benzodiazepine (PBDT) derivatives was synthesized from isatoic anhydride, and their cytotoxicity against the MRC-5 and Mahlavu cell lines was evaluated. The results suggest that compound PBDT-7i with the meta-trifluoromethylbenzoyl substituent...

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Detalles Bibliográficos
Autores principales: Sorra, Kumaraswamy, Chang, Chi-Fen, Pusuluri, Srinivas, Mukkanti, Khagga, Laiu, Min-Chiau, Bao, Bo-Ying, Su, Chia-Hao, Chuang, Ta-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269039/
https://www.ncbi.nlm.nih.gov/pubmed/22832878
http://dx.doi.org/10.3390/molecules17088762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269039/
https://www.ncbi.nlm.nih.gov/pubmed/22832878
http://dx.doi.org/10.3390/molecules17088762

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