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Synthesis and Cytotoxicity Testing of New Amido-Substituted Triazolopyrrolo[2,1-c][1,4]benzodiazepine (PBDT) Derivatives

A series of amido-substituted triazolopyrrolo[2,1-c][1,4]benzodiazepine (PBDT) derivatives was synthesized from isatoic anhydride, and their cytotoxicity against the MRC-5 and Mahlavu cell lines was evaluated. The results suggest that compound PBDT-7i with the meta-trifluoromethylbenzoyl substituent...

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Detalles Bibliográficos
Autores principales:	Sorra, Kumaraswamy, Chang, Chi-Fen, Pusuluri, Srinivas, Mukkanti, Khagga, Laiu, Min-Chiau, Bao, Bo-Ying, Su, Chia-Hao, Chuang, Ta-Hsien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269039/ https://www.ncbi.nlm.nih.gov/pubmed/22832878 http://dx.doi.org/10.3390/molecules17088762

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