A novel enhancer near the Pitx1 gene influences development and evolution of pelvic appendages in vertebrates

Vertebrate pelvic reduction is a classic example of repeated evolution. Recurrent loss of pelvic appendages in sticklebacks has previously been linked to natural mutations in a pelvic enhancer that maps upstream of Pitx1. The sequence of this upstream PelA enhancer is not conserved to mammals, so we...

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Detalles Bibliográficos
Autores principales: Thompson, Abbey C, Capellini, Terence D, Guenther, Catherine A, Chan, Yingguang Frank, Infante, Carlos R, Menke, Douglas B, Kingsley, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269122/
https://www.ncbi.nlm.nih.gov/pubmed/30499775
http://dx.doi.org/10.7554/eLife.38555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269122/
https://www.ncbi.nlm.nih.gov/pubmed/30499775
http://dx.doi.org/10.7554/eLife.38555

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