Temperature sensitive point mutations in fission yeast tropomyosin have long range effects on the stability and function of the actin-tropomyosin copolymer

The actin cytoskeleton is modulated by regulatory actin-binding proteins which fine-tune the dynamic properties of the actin polymer to regulate function. One such actin-binding protein is tropomyosin (Tpm), a highly-conserved alpha-helical dimer which stabilises actin and regulates interactions wit...

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Detalles Bibliográficos
Autores principales: Johnson, Chloe A., Brooker, Holly R., Gyamfi, Irene, O'Brien, Jennifer, Ashley, Brogan, Brazier, Jodie E., Dean, Annette, Embling, James, Grimsey, Elisabeth, Tomlinson, Alice C., Wilson, Elliot G., Geeves, Michael A., Mulvihill, Daniel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269162/
https://www.ncbi.nlm.nih.gov/pubmed/29080743
http://dx.doi.org/10.1016/j.bbrc.2017.10.109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269162/
https://www.ncbi.nlm.nih.gov/pubmed/29080743
http://dx.doi.org/10.1016/j.bbrc.2017.10.109

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