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Temperature sensitive point mutations in fission yeast tropomyosin have long range effects on the stability and function of the actin-tropomyosin copolymer
The actin cytoskeleton is modulated by regulatory actin-binding proteins which fine-tune the dynamic properties of the actin polymer to regulate function. One such actin-binding protein is tropomyosin (Tpm), a highly-conserved alpha-helical dimer which stabilises actin and regulates interactions wit...
Autores principales: | Johnson, Chloe A., Brooker, Holly R., Gyamfi, Irene, O'Brien, Jennifer, Ashley, Brogan, Brazier, Jodie E., Dean, Annette, Embling, James, Grimsey, Elisabeth, Tomlinson, Alice C., Wilson, Elliot G., Geeves, Michael A., Mulvihill, Daniel P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269162/ https://www.ncbi.nlm.nih.gov/pubmed/29080743 http://dx.doi.org/10.1016/j.bbrc.2017.10.109 |
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