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The Genetic Architecture of Diet‐Induced Hepatic Fibrosis in Mice

We report the genetic analysis of a “humanized” hyperlipidemic mouse model for progressive nonalcoholic steatohepatitis (NASH) and fibrosis. Mice carrying transgenes for human apolipoprotein E*3‐Leiden and cholesteryl ester transfer protein and fed a “Western” diet were studied on the genetic backgr...

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Detalles Bibliográficos
Autores principales: Hui, Simon T., Kurt, Zeyneb, Tuominen, Iina, Norheim, Frode, C.Davis, Richard, Pan, Calvin, Dirks, Darwin L., Magyar, Clara E., French, Samuel W., Chella Krishnan, Karthickeyan, Sabir, Simon, Campos‐Pérez, Francisco, Méndez‐Sánchez, Nahum, Macías‐Kauffer, Luis, León‐Mimila, Paola, Canizales‐Quinteros, Samuel, Yang, Xia, Beaven, Simon W., Huertas‐Vazquez, Adriana, Lusis, Aldons J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269199/
https://www.ncbi.nlm.nih.gov/pubmed/29907965
http://dx.doi.org/10.1002/hep.30113