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Osteogenic niche in the regulation of normal hematopoiesis and leukemogenesis
The bone marrow microenvironment, also known as the bone marrow niche, is a complex network of cell types and acellular factors that supports normal hematopoiesis. For many years, leukemia was believed to be caused by a series of genetic hits to hematopoietic stem and progenitor cells, which transfo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269284/ https://www.ncbi.nlm.nih.gov/pubmed/30337364 http://dx.doi.org/10.3324/haematol.2018.197004 |