TP53 aberrations in chronic lymphocytic leukemia: an overview of the clinical implications of improved diagnostics

Chronic lymphocytic leukemia is associated with a highly heterogeneous disease course in terms of clinical outcomes and responses to chemoimmunotherapy. This heterogeneity is partly due to genetic aberrations identified in chronic lymphocytic leukemia cells such as mutations of TP53 and/or deletions...

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Detalles Bibliográficos
Autores principales: Campo, Elias, Cymbalista, Florence, Ghia, Paolo, Jäger, Ulrich, Pospisilova, Sarka, Rosenquist, Richard, Schuh, Anna, Stilgenbauer, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269313/
https://www.ncbi.nlm.nih.gov/pubmed/30442727
http://dx.doi.org/10.3324/haematol.2018.187583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269313/
https://www.ncbi.nlm.nih.gov/pubmed/30442727
http://dx.doi.org/10.3324/haematol.2018.187583

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