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TP53 aberrations in chronic lymphocytic leukemia: an overview of the clinical implications of improved diagnostics
Chronic lymphocytic leukemia is associated with a highly heterogeneous disease course in terms of clinical outcomes and responses to chemoimmunotherapy. This heterogeneity is partly due to genetic aberrations identified in chronic lymphocytic leukemia cells such as mutations of TP53 and/or deletions...
Autores principales: | Campo, Elias, Cymbalista, Florence, Ghia, Paolo, Jäger, Ulrich, Pospisilova, Sarka, Rosenquist, Richard, Schuh, Anna, Stilgenbauer, Stephan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269313/ https://www.ncbi.nlm.nih.gov/pubmed/30442727 http://dx.doi.org/10.3324/haematol.2018.187583 |
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