Cardiac specific PRMT1 ablation causes heart failure through CaMKII dysregulation

Dysregulation of Ca(2+)/calmodulin-dependent protein kinase (CaMK)II is closely linked with myocardial hypertrophy and heart failure. However, the mechanisms that regulate CaMKII activity are incompletely understood. Here we show that protein arginine methyltransferase 1 (PRMT1) is essential for pre...

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Detalles Bibliográficos
Autores principales: Pyun, Jung-Hoon, Kim, Hyun-Ji, Jeong, Myong-Ho, Ahn, Byeong-Yun, Vuong, Tuan Anh, Lee, Dong I., Choi, Seri, Koo, Seung-Hoi, Cho, Hana, Kang, Jong-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269446/
https://www.ncbi.nlm.nih.gov/pubmed/30504773
http://dx.doi.org/10.1038/s41467-018-07606-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269446/
https://www.ncbi.nlm.nih.gov/pubmed/30504773
http://dx.doi.org/10.1038/s41467-018-07606-y

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