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Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors

A complex interplay of intrinsic factors and extrinsic signalling pathways controls both cell lineage commitment and maintenance of cell identity. Loss of defined cellular states is the cause of many different cancers, including pancreatic cancer. Recent findings suggest a clinical role for the cons...

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Detalles Bibliográficos
Autores principales: Escot, Sophie, Willnow, David, Naumann, Heike, Di Francescantonio, Silvia, Spagnoli, Francesca M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269453/
https://www.ncbi.nlm.nih.gov/pubmed/30504829
http://dx.doi.org/10.1038/s41467-018-07474-6