Alpha-tubulin acetyltransferase/MEC-17 regulates cancer cell migration and invasion through epithelial–mesenchymal transition suppression and cell polarity disruption

MEC-17, a newly identified alpha-tubulin-N-acetyltransferase 1, serves as the major α-tubulin acetyltransferase to promote α-tubulin acetylation in vitro and in vivo. Alteration of α-tubulin acetylation may be involved in morphology regulation, cell migration, and tumour metastasis. However, MEC-17’...

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Detalles Bibliográficos
Autores principales: Lee, Cheng-Che, Cheng, Yun-Ching, Chang, Chi-Yen, Lin, Chi-Min, Chang, Jang-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269487/
https://www.ncbi.nlm.nih.gov/pubmed/30504808
http://dx.doi.org/10.1038/s41598-018-35392-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269487/
https://www.ncbi.nlm.nih.gov/pubmed/30504808
http://dx.doi.org/10.1038/s41598-018-35392-6

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