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miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC

Non-small cell lung carcinoma (NSCLC) is leading cause of cancer-related deaths in the world. The Tumor Suppressor Candidate 3 (TUSC3) at chromosome 8p22 known to be frequently deleted in cancer is often found to be deleted in advanced stage of solid tumors. However, the role of TUSC3 still remains...

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Detalles Bibliográficos
Autores principales: Jeon, Young-Jun, Kim, Taewan, Park, Dongju, Nuovo, Gerard J., Rhee, Siyeon, Joshi, Pooja, Lee, Bum-Kyu, Jeong, Johan, Suh, Sung-suk, Grotzke, Jeff E., Kim, Sung-Hak, Song, Jieun, Sim, Hosung, Kim, Yonghwan, Peng, Yong, Jeong, Youngtae, Garofalo, Michela, Zanesi, Nicola, Kim, Jonghwan, Liang, Guang, Nakano, Ichiro, Cresswell, Peter, Nana-Sinkam, Patrick, Cui, Ri, Croce, Carlo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269493/
https://www.ncbi.nlm.nih.gov/pubmed/30504895
http://dx.doi.org/10.1038/s41467-018-07561-8