miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC

Non-small cell lung carcinoma (NSCLC) is leading cause of cancer-related deaths in the world. The Tumor Suppressor Candidate 3 (TUSC3) at chromosome 8p22 known to be frequently deleted in cancer is often found to be deleted in advanced stage of solid tumors. However, the role of TUSC3 still remains...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeon, Young-Jun, Kim, Taewan, Park, Dongju, Nuovo, Gerard J., Rhee, Siyeon, Joshi, Pooja, Lee, Bum-Kyu, Jeong, Johan, Suh, Sung-suk, Grotzke, Jeff E., Kim, Sung-Hak, Song, Jieun, Sim, Hosung, Kim, Yonghwan, Peng, Yong, Jeong, Youngtae, Garofalo, Michela, Zanesi, Nicola, Kim, Jonghwan, Liang, Guang, Nakano, Ichiro, Cresswell, Peter, Nana-Sinkam, Patrick, Cui, Ri, Croce, Carlo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269493/
https://www.ncbi.nlm.nih.gov/pubmed/30504895
http://dx.doi.org/10.1038/s41467-018-07561-8

Ejemplares similares

Ejemplares similares