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Sensitization of renal carcinoma cells to TRAIL-induced apoptosis by rocaglamide and analogs

Rocaglamide has been reported to sensitize several cell types to TRAIL-induced apoptosis. In recent years, advances in synthetic techniques have led to generation of novel rocaglamide analogs. However, these have not been extensively analyzed as TRAIL sensitizers, particularly in TRAIL-resistant ren...

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Detalles Bibliográficos
Autores principales: Nalli, Ancy D., Brown, Lauren E., Thomas, Cheryl L., Sayers, Thomas J., Porco, John A., Henrich, Curtis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269514/
https://www.ncbi.nlm.nih.gov/pubmed/30504817
http://dx.doi.org/10.1038/s41598-018-35908-0