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Modified VEGF-A mRNA induces sustained multifaceted microvascular response and accelerates diabetic wound healing

Capable of mediating efficient transfection and protein production without eliciting innate immune responses, chemically modified mRNA holds great potential to produce paracrine factors at a physiologically beneficial level, in a spatiotemporally controlled manner, and with low toxicity. Although hi...

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Detalles Bibliográficos
Autores principales: Sun, Naidi, Ning, Bo, Hansson, Kenny M., Bruce, Anthony C., Seaman, Scott A., Zhang, Chenchu, Rikard, Michaela, DeRosa, Christopher A., Fraser, Cassandra L., Wågberg, Maria, Fritsche-Danielson, Regina, Wikström, Johannes, Chien, Kenneth R., Lundahl, Anna, Hölttä, Mikko, Carlsson, Leif G., Peirce, Shayn M., Hu, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269526/
https://www.ncbi.nlm.nih.gov/pubmed/30504800
http://dx.doi.org/10.1038/s41598-018-35570-6