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Modified VEGF-A mRNA induces sustained multifaceted microvascular response and accelerates diabetic wound healing
Capable of mediating efficient transfection and protein production without eliciting innate immune responses, chemically modified mRNA holds great potential to produce paracrine factors at a physiologically beneficial level, in a spatiotemporally controlled manner, and with low toxicity. Although hi...
Autores principales: | Sun, Naidi, Ning, Bo, Hansson, Kenny M., Bruce, Anthony C., Seaman, Scott A., Zhang, Chenchu, Rikard, Michaela, DeRosa, Christopher A., Fraser, Cassandra L., Wågberg, Maria, Fritsche-Danielson, Regina, Wikström, Johannes, Chien, Kenneth R., Lundahl, Anna, Hölttä, Mikko, Carlsson, Leif G., Peirce, Shayn M., Hu, Song |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269526/ https://www.ncbi.nlm.nih.gov/pubmed/30504800 http://dx.doi.org/10.1038/s41598-018-35570-6 |
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