Evaluation of droplet digital PCR and next generation sequencing for characterizing DNA reference material for KRAS mutation detection

KRAS gene mutations are predictive markers of non-response to anti-epidermal growth factor receptor. An increasing number of techniques are being developed to detect KRAS mutations. To obtain consistent and comparable results, a traceable reference material (RM) is necessary for validation the routi...

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Detalles Bibliográficos
Autores principales: Dong, Lianhua, Wang, Shangjun, Fu, Boqiang, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269532/
https://www.ncbi.nlm.nih.gov/pubmed/30504843
http://dx.doi.org/10.1038/s41598-018-27368-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269532/
https://www.ncbi.nlm.nih.gov/pubmed/30504843
http://dx.doi.org/10.1038/s41598-018-27368-3

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