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Evaluation of droplet digital PCR and next generation sequencing for characterizing DNA reference material for KRAS mutation detection
KRAS gene mutations are predictive markers of non-response to anti-epidermal growth factor receptor. An increasing number of techniques are being developed to detect KRAS mutations. To obtain consistent and comparable results, a traceable reference material (RM) is necessary for validation the routi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269532/ https://www.ncbi.nlm.nih.gov/pubmed/30504843 http://dx.doi.org/10.1038/s41598-018-27368-3 |