Administration of antibiotics contributes to cholestasis in pediatric patients with intestinal failure via the alteration of FXR signaling

The link between antibiotic treatment and IF-associated liver disease (IFALD) is unclear. Here, we study the effect of antibiotic treatment on bile acid (BA) metabolism and investigate the involved mechanisms. The results showed that pediatric IF patients with cholestasis had a significantly lower a...

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Detalles Bibliográficos
Autores principales: Xiao, Yongtao, Zhou, Kejun, Lu, Ying, Yan, Weihui, Cai, Wei, Wang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269533/
https://www.ncbi.nlm.nih.gov/pubmed/30504803
http://dx.doi.org/10.1038/s12276-018-0181-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269533/
https://www.ncbi.nlm.nih.gov/pubmed/30504803
http://dx.doi.org/10.1038/s12276-018-0181-3

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