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Administration of antibiotics contributes to cholestasis in pediatric patients with intestinal failure via the alteration of FXR signaling
The link between antibiotic treatment and IF-associated liver disease (IFALD) is unclear. Here, we study the effect of antibiotic treatment on bile acid (BA) metabolism and investigate the involved mechanisms. The results showed that pediatric IF patients with cholestasis had a significantly lower a...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269533/ https://www.ncbi.nlm.nih.gov/pubmed/30504803 http://dx.doi.org/10.1038/s12276-018-0181-3 |