Novel Colchicine Analogues Target Mitochondrial PT Pores Using Free Tubulins and Induce ROS-Mediated Apoptosis in Cancerous Lymphocytes

B-acute lymphoblastic leukemia (B-ALL) is the frequent pediatric malignity. Chemotherapy is the most practical approaches to deal with such malignancies. Microtubule-targeted agents are one of the most strategic drugs which formerly used in chemotherapy. Although colchicine-binding anti-tubulin agen...

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Detalles Bibliográficos
Autores principales: Aghvami, Marjan, Eshghi, Peyman, Zarei, Mohammad Hadi, Arefi, Hadi, Sattari, Fatemeh, Zarghi, Afshin, Pourahmad, Jalal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269570/
https://www.ncbi.nlm.nih.gov/pubmed/30568705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269570/
https://www.ncbi.nlm.nih.gov/pubmed/30568705

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