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Pixel Selection by Successive Projections Algorithm Method in Multivariate Image Analysis for a QSAR Study of Antimicrobial Activity for Cephalosporins and Design New Cephalosporins
Thirty-one Cephalosporin compounds were modeled using the multivariate image analysis and applied to the quantitative structure activity relationship (MIA-QSAR) approach. The acid dissociation constants (pK(a)) of cephalosporins play a fundamental role in the mechanism of activity of cephalosporins....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shaheed Beheshti University of Medical Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269580/ https://www.ncbi.nlm.nih.gov/pubmed/30568684 |