Pixel Selection by Successive Projections Algorithm Method in Multivariate Image Analysis for a QSAR Study of Antimicrobial Activity for Cephalosporins and Design New Cephalosporins

Thirty-one Cephalosporin compounds were modeled using the multivariate image analysis and applied to the quantitative structure activity relationship (MIA-QSAR) approach. The acid dissociation constants (pK(a)) of cephalosporins play a fundamental role in the mechanism of activity of cephalosporins....

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Detalles Bibliográficos
Autores principales: Amraei, Ahmadreza, Niazi, Ali, Alimmoradi, Mohammad, Delfan, Bahram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269580/
https://www.ncbi.nlm.nih.gov/pubmed/30568684

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