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Aptamer-based Targeted Delivery of miRNA let-7d to Gastric Cancer Cells as a Novel Anti-Tumor Therapeutic Agent

miRNAs as one of the potential therapeutic agents have been recently considered for cancer treatment. AS1411 (aptNCL) is a DNA aptamer specifically binding to nucleolin protein on the cancer cell surface with antiproliferative effect. The aim of the study was to develop a conjugate consisting of apt...

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Detalles Bibliográficos
Autores principales: Daei, Puyan, Ramezanpour, Mahsa, Khanaki, Korosh, Tabarzad, Maryam, Nikokar, Iraj, Hedayati CH, Mojtaba, Elmi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269583/
https://www.ncbi.nlm.nih.gov/pubmed/30568710