Mechanistic Approach for Thioridazine-Induced Hepatotoxicity and Potential Benefits of Melatonin and/or Coenzyme Q10 on Freshly Isolated Rat Hepatocytes

Thioridazine (TZ) is used mainly in the treatment of schizophrenia. However, hepatotoxicity as a life-threatening adverse effect is associated with its clinical use. In this context, we examined the cytotoxic mechanisms of TZ on freshly isolated rat hepatocytes to better understanding of the pathoge...

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Detalles Bibliográficos
Autores principales: Eftekhari, Aziz, Ahmadian, Elham, Azarmi, Yadollah, Parvizpur, Alireza, Khalili Fard, Javad, Eghbal, Mohammad Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269589/
https://www.ncbi.nlm.nih.gov/pubmed/30568704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269589/
https://www.ncbi.nlm.nih.gov/pubmed/30568704

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